Marc Scoffoni graduated from the National Conservatory in Paris and the Guildhall School of Music in London. He was awarded by the ADAMI as the 2005 up-and-coming lyric artist. He took part in the Academy of the Aix-en-Provence Festival. Between 2011 and 2013, he was a member of the « Young Ensemble » at the Grand-Théâtre in Geneva.

On stage, he sang such roles as Papageno from Die Zauberflöte, Guglielmo from Cosí fan tutte, Masetto and Don Giovanni, Nardo from La Finta Giardiniera, Figaro from Il Barbiere di Siviglia, Raimbaud from Le Comte Ory, Malatesta from Don Pasquale, Dandini from La Cenerentola, Gasparo from Rita by Donizetti, Germont from La Traviata, Fléville, Fouquier-Tinville and Roucher from Andrea Chénier, Michonnet from Adriana Lecouvreur, Alfio from Cavalleria Rusticana, Sharpless from Madama Butterfly, Rambaldo from La Rondine, Alessio from La Sonnambula.

In the French repertoire, he performed as Escamillo from Carmen, Frédéric from Lakmé, Valentin from Faust by Gounod, Albert and Le Bailli from Werther, Schlémil and Hermann from Les Contes d’Hoffmann, Brétigny from Manon, Le Chevalier Des Grieux from Le Portrait de Manon, Mercutio from Roméo et Juliette, l’Officier from Dialogues des Carmélites, the Clock and the Cat from L’Enfant et les Sortilèges, Jahel from Le Roi d’Ys, Clavaroche from Fortunio, Sganarelle from Le Médecin Malgré Lui, Pausanias from Une Education Manquée, Roger from Ciboulette, Robert from La Fille du Tambour Major, Jupiter from Orphée aux Enfers, Gaspard from Das Land des Lächelns (French version), Le Vice-Roi from La Périchole, Gaveston from La Dame Blanche.